Interaction of insulin with prokinetic drugs in STZ-induced diabetic mice
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چکیده
منابع مشابه
Bezafibrate Improves Insulin Sensitivity and Metabolic Flexibility in STZ-Induced Diabetic Mice.
Bezafibrate (BEZ), a pan activator of peroxisome proliferator-activated receptors (PPARs), has been generally used to treat hyperlipidemia for decades. Clinical trials with type 2 diabetes patients indicated that BEZ also has beneficial effects on glucose metabolism, although the underlying mechanisms of these effects remain elusive. Even less is known about a potential role for BEZ in treating...
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BACKGROUND & AIMS Metformin is currently the most widely used first-line hypoglycemic agent for diabetes mellitus. Besides glucose-lowering action, there is increasingly interest in the potential anti-inflammatory action of this drug. In the present study, we investigated the actions of metformin on experimental insulitis using STZ-induced diabetic mice. METHODS Mice with acute diabetes induc...
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Purpose: The aim of this study was to investigate effects of insulin and ascorbic acid on rate of Caspase – 3 activity and DNA Laddering in hippocampus of STZ-induced diabetic rats.Materials and Methods: Thirty male Wistar rats in five groups, 6 in each group: one control group (group C) and four diabetic groups [diabetic control (group D), treatment with insulin (group I), with ascorbic acid (...
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Diabetic neuropathic pain, an important micro vascular complication in diabetes mellitus, has been recognized as one of the most difficult types of pain to treat. Lack of understanding of etiology involved, inadequate relief, development of tolerance and potential toxicity of classical anti-nociceptive agents warrants the investigation of newer agents to relieve this pain. The aim of the presen...
متن کاملThe effect of fluoxetine on thermal hyperalgesia in STZ-induced diabetic mice: possible involvement of 5-HT1/2 receptors
Diabetic neuropathic pain, an important micro vascular complication in diabetes mellitus, has been recognized as one of the most difficult types of pain to treat. Lack of understanding of etiology involved, inadequate relief, development of tolerance and potential toxicity of classical anti-nociceptive agents warrants the investigation of newer agents to relieve this pain. The aim of the presen...
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ژورنال
عنوان ژورنال: World Journal of Gastrointestinal Pharmacology and Therapeutics
سال: 2013
ISSN: 2150-5349
DOI: 10.4292/wjgpt.v4.i2.28